Is there a way to integrate or link billing in Quickbooks with the Mikrotik program, this for the purpose of automatic signal cuts or activation for users?

Let me give you more details when using with QuickBooks Online, Viaje.

QuickBooks integrates with different kinds of application and eliminates tedious, and manual data entry. You'll want to contact the Mikrotik Support to see if you're able to link them with QuickBooks Online (QBO). 

You can also check out other applications that available and those that you can use with QuickBooks. To access them, follow the steps provided below:

1. Sign in to your QBO account.
2. Click Apps from the left menu.
3. Go to the Find Apps tab.
4. Click the Browse category button to filter the results.
    

Moreover, you may want to familiarize some of the main features in QBO. To learn how to personalise your company information, connect your bank or credit card accounts, import data and send invoice, check out this article for your reference:  Get Started With QuickBooks Online.

Leave a comment below if you have any concerns with integrating applications. I'd be more than happy to help. Have a nice day!

@viaje12022021-gm 

I don't see any interoperability between business applications and network devices. Unless you can create CLI in Mikrotik to generate and send data automatically to MS 365 Excel.