I need to refresh my windows11 installation so, will I loose the ability to reinstall my quickbook 2021 licence on the same computer

Make sure you can access CAMPS as Primary Contact and find your license information there beforehand.

However, I wouldn't recommend running QB Desktop on Win 11 for the time being until next year. If you are eligible, you should consider downgrading to Win 10 Home instead with the same license key for free.