I cannot open Profit and loss report, please help to check

It's good to see you here, @annie331,

Have you tried opening the report in a private window and check if the same thing happens there? Unexpected issues in QBO are most likely affected by the large data in the cache. This is because the regular browser will constantly accumulate data and will not remove its history automatically.

The incognito mode will not save any history, so it's a great place to identify issues in the browser. Use these keyboard shortcuts to launch a new private window:

• Google Chrome: press Ctrl + Shift + N  
• Mozilla Firefox: press Ctrl + Shift + P
• Safari: press Command + Shift + N

If it works there, clear the cache to resolve the issue in regular browsing. 

However, if the same thing happens, I highly recommend getting in touch with our Support Team to report the problem. To contact us, follow these steps below:

1. Go to the Help menu.
2. At the bottom click on Contact us.
3. Enter the keyword Account Management and Billing in the What can we help you with? box.
   
4. On the next screen, scroll down to How would you like to connect with us section.
5. Choose the contact option you want from the result.

Kindly update me on how it goes. I'll be right here if you need further assistance with QuickBooks Online reports. Have a nice day!