Hello Becmech,
I'm here to help you in setting up an employee's payroll.
When establishing an employee who lives and works in Indiana, you'll have to select Indiana as the state where they live and works. This ensures that the appropriate state taxes and other relevant payroll information are applied correctly.
For employees who live in Indiana but work in Illinois, you'll have to select Indiana as the state where the employee lives and Illinois as the state where the employee works. However, I recommend visiting Indiana state to know if they have a reciprocal agreement with Illinois on how to handle the employee's withholding taxes. This helps you ensure that you are in compliance with the Indiana and Illinois states.
Furthermore, you can check these articles as your guide in setting up employee's direct deposit:
I'm always around whenever you have payroll concerns.