(Error code: -81597, type: SYSTEM_ERROR)

I've got some troubleshooting steps to fix the error you've encountered in QuickBooks Online (QBO), claire-ryansteel.

The Error code: -81597 in QBO indicates the application or the web browser itself has become unresponsive or has stopped working. To better isolate this issue, we can log in to your account using an incognito browser. Private browser prevents saving cache and cookies that sometimes cause errors when running frequently visited websites. Here are the useful shortcut keys you can use to access one:

• Ctrl+ Shift + N for Google Chrome 
• Ctrl + Shift + P for Mozilla Firefox and Microsoft Edge 
• Command + Shift + N for Safari 

If it works go back to your regular browser and clear its cache. Clearing the cache or cookies is the best way to start fresh and ensure optimal performance. Otherwise, using other supported browsers can be a good alternative too.

Know that our door is open 24/7 in case you need further assistance with this error message or any QuickBooks-related. You can also mention me in the comment section below. This way, I'll be notified and can help you right away.